Low Vitamin D Increases Depression in Older Adults

Older adults who have low levels of vitamin D have a greater risk of developing depression, according to a new study published in the Journal of Clinical Endocrinology & Metabolism.

Researchers followed 531 women and 423 men aged 65 years and older who participated in the InCHIANTI Study in Tuscany, Italy. Serum 25(OH)D was measured at baseline. Depressive symptoms were assessed at baseline and at 3- and 6-year follow-ups using the Center for Epidemiological Studies-Depression Scale (CES-D). Depressed mood was defined as CES-D of 16 or higher. Analyses were stratified by sex and adjusted for relevant biomarkers and variables related to sociodemographics, somatic health and functional status.