No Scientific Evidence Detox Diets Offer Any Health Benefits

Detox, or detoxification, diets are popular, but they’re not scientifically proven.

Detox diets are touted as a way to remove toxins from the body. Specific detox diets vary — but typically a period of fasting is followed by a strict diet of raw vegetables, fruit and fruit juices, and water. In addition, some detox diets advocate using herbs and other supplements along with colon cleansing (enemas) to empty the intestines.

Some people report feeling more focused and energetic during and after detox diets. However, there’s little evidence that detox diets actually remove toxins from the body. Indeed, the kidneys and liver effectively filter and eliminate most ingested toxins. The benefits from a detox diet may actually come from avoiding highly processed foods that have solid fats and added sugar.

If you’re considering a detox diet, get the OK from your doctor first. It’s also important to consider possible side effects. Detox diets that severely limit protein or that require fasting, for example, can result in fatigue. Long-term fasting can result in vitamin and mineral deficiencies. Colon cleansing, which is often recommended as part of a detox plan, can cause cramping, bloating, nausea and vomiting. Dehydration also can be a concern.

Finally, keep in mind that fad diets aren’t a good long-term solution. For lasting results, your best bet is to eat a healthy diet based on fruits and vegetables, whole grains, and lean sources of protein.

Source: Mayo Clinic

Read more in The Globe and Mail….

Why this is the year you should ditch the desire to detox, cleanse …..

New Hybrid Snacks from Mister Donut in Japan

D & D stands for Donut & Danish. 4 different flavours are offered.

Plain

Caramel and Nuts

Strawberry

Banana and Chocolate

New Blood Test for Prostate Cancer

Vanderbilt University researcher William Mitchell, M.D., Ph.D., and colleagues in Germany and Canada have demonstrated a method for detecting “cell-free” tumor DNA in the bloodstream.

Mitchell believes the technique will be transformative in providing improved cancer diagnostics that can both predict treatment outcomes and monitor patient responses to therapy.

In a large retrospective study of blood samples, the researchers showed that the method, called a “liquid biopsy,” could accurately distinguish prostate cancer from normal controls without prior knowledge of the genetic “signature” of the tumors, and with over three times the sensitivity of current prostate-specific antigen (PSA) screening.

The study appears in the January issue of Clinical Chemistry (volume 61, page 239), which is dedicated to “Molecular Diagnostics: A Revolution in Progress.”

“Based on the reported data and work in progress, I believe the ‘liquid biopsy’ will revolutionize cancer diagnostics, not only before a patient begins therapy but also following patient responses to therapy,” said Mitchell, the paper’s corresponding author and professor of Pathology, Microbiology and Immunology.

The study collected serum from more than 200 patients with prostate cancer and more than 200 controls. The samples included PSA levels and prostate tissue biopsy grading, called the Gleason score.

The researchers reported that the technique distinguished prostate cancer from normal controls with 84-percent accuracy, and cancer from benign hyperplasia and prostatitis with an accuracy of 91 percent.

Because the method quantifies the inherent chromosomal instability of cancer and can be followed as a function of time without having to do an invasive tissue biopsy, it is called a “liquid biopsy.”

It’s been known for many years that dying cells, including tumor cells, shed DNA into the bloodstream.

But only recently has technology, notably “next-generation sequencing,” made it possible to reliably distinguish and quantify cancer-specific DNA from normal controls by the identification and chromosomal location of billions of specific DNA fragments present in blood as cell-free DNA.

The prostate cancer study identified 20 “hotspots” of greatest chromosomal instability as additions or deletions in less than 0.5 percent of the total DNA present in human chromosomes.

While researchers around the world are working on their own “liquid biopsies,” Mitchell said the group’s technique takes a broader approach. It examines the entire genome rather than known specific gene point mutations.

Robust mutation panels vastly improve monitoring since cancer cells are constantly deleting chromosomal DNA and liquid biopsies with only one or two mutations will allow cancer cell escape variants to go undetected, he said.

Since the entire genome was surveyed, the researchers were able to identify a non-coding region of the genome as a “hotspot,” which may be generating previously unrecognized chromosomal control elements in prostate cancer.

The other 19 “hotspots” were rich in genes involved in replication and cell control processes that are highly relevant to cancer.

“Since cell-free DNA has a relatively short half-life in the circulation, sequencing of cell-free DNA soon after therapy may be used to detect minimal residual disease in solid tumors,” Mitchell said.

The researchers reported similar results in a study of breast cancer at the 2013 annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago. Mitchell further predicted that liquid biopsies will quantify immediate tumor responses to therapy.

Source: EurekAlert!

Chocolate Brownies with Beet

Ingredients

2 medium-sized beets, peeled and chopped
180 g bittersweet baking chocolate, chopped
1/4 cup unsalted butter
2 large eggs, preferably room temperature
3/4 cup whole-wheat flour
2/3 cup sugar
1/3 cup plain, low-fat yogurt
1/3 cup unsweetened cocoa powder
1 tsp cinnamon
1 tsp vanilla extract
1/2 tsp baking powder
1/4 tsp salt
1/2 cup chopped pecans or walnuts (optional)

Method

  1. Steam or boil beets until very tender, about 30 minutes. Place them in a food processor and purée. Set aside to cool.
  2. Preheat oven to 350°F. Lightly grease an 8-in. square baking pan.
  3. Place chocolate and butter in a metal bowl over a pot of simmering water, and stir until melted (or place in a microwave-safe dish and microwave on high in 25-second increments, stirring between each interval, until melted).
  4. Remove from heat, transfer to a large bowl and mix in eggs, one at a time.
  5. Gently stir in beet purée, flour, sugar, yogurt, cocoa powder, cinnamon, vanilla, baking powder and salt. Fold in nuts if using. Pour mixture into pan and spread evenly. Bake for 20 minutes or until a toothpick inserted into centre comes out clean. Let cool before slicing.

Makes 16 brownies.

Source: Best Health magazine


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