Hearty Egg Sandwich of Eggslut in Shinjuku, Japan

Sandwiched between the brioche bun are creamy scrambled egg, cheddar cheese and caramelized onions with Sirracha mayo seasoning.

The price of the sandwich is 880 yen (plus tax) and a combo set with orange juice is 1,260 yen (plus tax).

Simple Pork Schnitzel

Ingredients

4 pork escalopes, about 150 g each, trimmed of fat
4 tbsp plain flour
2 eggs, beaten
100 g fresh breadcrumbs
700 g carrots, cut into batons
2 tbsp olive oil
30 g butter

Cashew Nut Pesto

6 sun-dried tomatoes from a jar, drained
60 g cashew nuts
50 g finely grated Parmesan
1 small red pepper, seeded and roughly chopped
1 garlic clove, crushed
50 ml olive oil
salt and pepper

Basil Rice

200 g basmati rice
25 g bunch of basil, leaves only
1 tbsp olive oil
juice of 1/2 lemon

Method

  1. First make the pesto. Place the sun-dried tomatoes, cashew nuts, Parmesan, red pepper, garlic and some seasoning in a food processor and pulse to combine. Add the olive oil and pulse again until you have a lovely orangey paste.
  2. Prepare the pork schnitzels by covering the escalopes with cling film or baking paper and bashing out each one on a board, using a meat mallet or rolling pin.
  3. Arrange your dipping ingredients in shallow bowls: flour in one, beaten eggs in another and breadcrumbs in another and lightly season each one. Dip each bashed escalope first in flour, then egg, then breadcrumbs and place on a tray until ready to cook.
  4. Start cooking the rice in a large pan of boiling salted water. Keep checking the rice, but it should be ready after about 8-10 minutes.
  5. Steam or boil the carrots to your liking.
  6. Blitz the basil leaves, olive oil and lemon juice to make a basil oil. Set aside.
  7. Heat a large non-stick frying pan over a medium-high heat and add the oil and butter. Wait for it to stop sizzling and then add the schnitzels. Fry gently for 3-4 minutes on each side, until golden. Drain on kitchen paper.
  8. Mix the basil oil through the drained rice. Toss the carrots in the cashew nut pesto. Use as much or as little as you like — any leftover pesto will keep for a good few days in the fridge and can be used for pasta, in wraps or drizzled over a bowl of soup.

Makes 4 servings.

Source: My Family Kitchen

Understanding the Basics of ‘Herd Immunity’ in Disease Transmission

Dr. Eduardo Sanchez wrote . . . . . . . . .

Recently I heard a medical “expert” on the news incorrectly define the term “herd immunity.” It’s a new phrase for many people, but we’re hearing about it more and more, so it’s important to understand exactly what it is.

First, let’s discuss how immunity works for individuals. A person can become immune (or resistant) after exposure to a disease-causing agent, such as the coronavirus causing COVID-19 in this case. The process of becoming immune includes the production of antibodies specific to the virus for future protection.

This production typically happens when a person develops the symptoms of the viral disease, but also may occur without symptoms. Irrespective of the symptoms, after significant exposure and time to develop the antibodies, a person becomes immune to that specific virus. In other words, the person is naturally “protected.”

If a large group of people – the herd – is immune to a virus, then an individual in the middle of this group is unlikely to become infected. The virus has a very hard time getting through the herd. Herd immunity, then, happens when people in a community are protected from a virus and its associated disease to a degree that people who are not immune are still protected because of the high population immunity.

Herd immunity can slow the spread of a contagious virus. Herd immunity can be alternatively achieved by vaccinating people if there is an available vaccine (or vaccines). Treatments that may be discovered and developed will help prevent progression of disease, help people recover from COVID-19 and will probably add to herd immunity.

Herd immunity is disease-specific and is influenced by the ease with which the disease spreads from person to person, or the level of contagiousness. The specifics about coronavirus and herd immunity are not yet characterized. Regardless of the specifics, achieving herd immunity by the repeated process of infection of one person, recovery and immunity will take a long time – many, many months or even years.

It will take a long time to achieve worldwide herd immunity. It may take less time in some cities or countries, but it will take time. Those individuals who are immune will be able to get back to work and be protected from reinfection and, probably, not transmit the virus or disease.

Source: American Heart Association

New York Hospitals Treating Coronavirus Patients with Vitamin C

Lorena Mongelli and Bruce Golding wrote . . . . . . . . .

Seriously sick coronavirus patients in New York state’s largest hospital system are being given massive doses of vitamin C — based on promising reports that it’s helped people in hard-hit China, The Post has learned.

Dr. Andrew G. Weber, a pulmonologist and critical-care specialist affiliated with two Northwell Health facilities on Long Island, said his intensive-care patients with the coronavirus immediately receive 1,500 milligrams of intravenous vitamin C.

Identical amounts of the powerful antioxidant are then readministered three or four times a day, he said.

Each dose is more than 16 times the National Institutes of Health’s daily recommended dietary allowance of vitamin C, which is just 90 milligrams for adult men and 75 milligrams for adult women.

The regimen is based on experimental treatments administered to people with the coronavirus in Shanghai, China, Weber said.

“The patients who received vitamin C did significantly better than those who did not get vitamin C,” he said.

“It helps a tremendous amount, but it is not highlighted because it’s not a sexy drug.”

A spokesman for Northwell — which operates 23 hospitals, including Lenox Hill Hospital on Manhattan’s Upper East Side — said vitamin C was being “widely used” as a coronavirus treatment throughout the system, but noted that medication protocols varied from patient to patient.

“As the clinician decides,” spokesman Jason Molinet said.

About 700 patients are being treated for coronavirus across the hospital network, Molinet said, but it’s unclear how many are getting the vitamin C treatment.

The vitamin C is administered in addition to such medicines as the anti-malaria drug hydroxychloroquine, the antibiotic azithromycin, various biologics and blood thinners, Weber said.

As of Tuesday, New York hospitals have federal permission to give a cocktail of hydroxychloroquine and azithromycin to desperately ill patients on a “compassionate care” basis.

President Trump has tweeted that the unproven combination therapy has “a real chance to be one of the biggest game changers in the history of medicine.”

Weber, 34, said vitamin C levels in coronavirus patients drop dramatically when they suffer sepsis, an inflammatory response that occurs when their bodies overreact to the infection.

“It makes all the sense in the world to try and maintain this level of vitamin C,” he said.

A clinical trial on the effectiveness of intravenous vitamin C on coronavirus patients began Feb. 14 at Zhongnan Hospital in Wuhan, China, the epicenter of the pandemic.

The randomized, triple-blind study will involve an estimated 140 participants and is expected to be complete by Sept. 30, according to information posted on the US National Library of Medicine’s website.

Source: NY Post

Dirty Air Might Raise Your Odds for Dementia

Alan Mozes wrote . . . . . . . . .

Smog drives up dementia risk, particularly for older men and women with heart disease, according to a new Swedish study.

For more than a decade, researchers tracked exposure to air pollution and dementia cases among nearly 3,000 Stockholm residents aged 60 and up.

Lead author Dr. Giulia Grande noted that exposure to dirty air has long been linked to an increased risk for lung and heart disease.

“More recently, several research groups have started to focus on the damages of air pollution on the brain — for example, its impact on cognitive functions in older adults,” she said.

The current research builds on that work. Participants were 74 years old on average and nearly two-thirds were women. All were free of dementia when the study began in 2001; they were tracked until 2013.

With strict air pollution rules in place, Stockholm has relatively good ambient air quality, said Grande, of the Aging Research Center at the Karolinska Institute and Stockholm University.

Her team pegged the city’s average annual pollution levels at about 2.5 microns of particulate matter or less — a level considered “low” by international standards.

Still, more than 12% of participants (364) developed dementia over the study period, the findings showed.

“And we found that people continuously exposed to higher levels of air pollution were at increased risk of dementia, as compared with those exposed to lower levels,” Grande said. That link was especially strong among participants who had a history of heart failure, ischemic heart disease or stroke.

Almost half of the pollution-related cases of dementia were connected to stroke, Grande said.

The findings dovetail with other research that has linked cardiovascular disease to a more rapid rate of cognitive (“thinking”) decline.

But why would air pollution increase dementia risk in the first place?

“Unfortunately, the biological mechanisms through which air pollution affects the brain are not completely understood,” Grande said. “But several pathways are possible.”

One possibility is that after inhaled pollutants penetrate the brain, they speed up accumulation of plaques that increase dementia risk, she said.

Poor air quality could also have an indirect effect, Grande added. Air pollution is an established risk to heart health and an “important trigger” for heart attacks and stroke. So, it could be the onset of heart disease that paves the way for development of dementia, she said.

That line of thinking made sense to Dr. Jesus Araujo, director of environmental cardiology at the David Geffen School of Medicine at UCLA. He said the kind of vascular damage brought on by heart disease may be an essential pre-requisite for dementia.

Araujo added that extensive evidence indicates that air pollution can trigger inflammation and hardening of the arteries (atherosclerosis), while also throwing the immune system out of whack (oxidative stress).

All of these factors “are important in the development of both cardiovascular disease and dementia,” according to Araujo, who was not involved with the new study.

Grande said the findings are one more reason to strengthen existing air-quality laws.

“By 2050, 68% of the world population is expected to live in urban areas, being continuously exposed to air pollution,” she pointed out. Her team projects that global dementia numbers will triple by 2050.

“Together with the worldwide aging of the population, this poses global challenges when it comes to preventive strategies for dementia,” Grande said. “So establishing and characterizing the relationship between air pollution and dementia has enormous impact.”

The report was published online in JAMA Neurology.

Source: HealthDay


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