Chuckles of the Day




Birthday Wish

A man asked his wife, “What would you most like for your birthday?”

She said, “I’d love to be ten again.”

On the morning of her birthday, he got her up bright and early and off they went to a theme park. He put her on every ride in the park–the Death Slide, The Screaming Loop, the Wall of Fear. Everything.

She staggered out of the theme park five hours later, her head reeling and her stomach upside down.

Into McDonalds they went, where she was given a Double Big Mac with extra fries and a strawberry shake. Then off to a theater to see Star Wars”-more burgers, popcorn, cola and sweets.

At last she staggered home with her husband and collapsed into bed.

Her husband leaned over and asked, “Well, dear, what was it like being ten again!”

One eye opened and she groaned, “Actually I meant dress size 10.”

* * * * * * *

Elderly Couple

A guy was invited to some old friends’ home for dinner.

His buddy preceded every request to his wife by endearing terms, calling her Honey, My Love, Darling, Sweetheart, Pumpkin, etc.

He was impressed since the couple had been married almost 70 years.

While the wife was off in the kitchen he said to his buddy, “I think it’s wonderful that after all the years you’ve been married, you still call your wife those pet names”.

His buddy hung his head. “To tell you the truth, I forgot her name about ten years ago.”




New Drug Shows Real Promise Against Celiac Disease

Amy Norton wrote . . . . . . . . .

An experimental drug can prevent intestinal damage caused by celiac disease, an early trial has found — raising hopes that it could become the first medication for the serious digestive disorder.

With celiac disease, the immune system attacks the lining of the small intestine when a genetically susceptible person eats gluten — a protein found in wheat, rye and barley.

The symptoms of celiac include diarrhea, abdominal pain, fatigue and weight loss. Underlying it all is an aberrant immune system attack that damages hair-like structures in the intestinal lining called villi. Villi absorb nutrients from food, so people with celiac can become malnourished and develop problems like anemia and thinning bones.

Right now, the only treatment is “rigorous avoidance of even traces of gluten in the daily diet,” said lead researcher Dr. Detlef Schuppan.

But a lifelong gluten-free diet is difficult to maintain, said Schuppan, a professor at the University Medical Center of Johannes Gutenberg University, in Germany.

Gluten can lurk in many processed foods, from pasta and breakfast cereals to sauces and soups to energy bars and chips.

Beyond being a practical burden, the strict diet is a “social and psychological” one as well, Schuppan noted.

And even when patients manage to adhere to it, he said, some can still have intestinal inflammation and symptoms.

The new study, published July 1 in the New England Journal of Medicine, looked at whether an experimental drug can prevent that intestinal damage.

The drug, dubbed ZED1227, inhibits the activity of an enzyme called transglutaminase 2 (TG2) in the intestines, Schuppan explained. TG2 plays a key role in the autoimmune response that marks celiac.

The trial, which was funded by drugmaker Dr. Falk Pharma, enrolled 163 adults with celiac disease who’d been successful with a gluten-free diet for at least a year.

The researchers randomly assigned the patients to one of four groups: three were given various doses of ZED1227 to take every morning for six weeks; the fourth took placebo pills.

Thirty minutes after each morning dose, the study patients ate a biscuit containing a moderate amount of gluten, as a way to test the drug’s ability to block gluten-induced inflammation.

After six weeks, the trial found, patients on any dose of the drug showed fewer signs of intestinal damage, versus the placebo group. As for side effects, skin rash was the only symptom more common among medication users; that was seen in 8% of patients on the highest dose.

Dr. Joseph Murray, a gastroenterologist at the Mayo Clinic, called the findings “encouraging.”

The trial “proves that blocking this key enzyme is feasible,” said Murray, who is also a medical advisor to the Celiac Disease Foundation.

Whether that will also lessen patients’ symptoms and improve their quality of life remains to be seen in larger studies, Murray said.

Like Schuppan, he noted that gluten-free diets are tough to maintain, and are not always enough on their own.

“About 30% of patients continue have substantial issues despite doing their best on a gluten-free diet,” Murray said.

Those patients will be the focus of future research. Schuppan said his team is planning a trial that will test ZED1227 in celiac disease patients who are not completely responding to a gluten-free diet.

If ZED1227 or any other medication becomes available for celiac, that does not spell the end of the gluten-free diet.

According to Murray, it’s likely patients will still have to follow diet restrictions. But, especially given the difficulty of avoiding gluten entirely, medication should make people’s lives easier, he said.

“There is real hope we will have additional treatments for celiac, which heretofore has placed the entire burden of care on the patient,” Murray said.

Roughly 1% of the world’s population has celiac disease, according to the Celiac Disease Foundation. In the United States, it’s estimated that 2.5 million people are undiagnosed.

Source: HealthDay

In Pictures: Popular Greek Food

Keftedes

Soutzoukakia

Moussaka

Pastitsio

Koulouria

Bougatsa

Souvlaki

Most Americans Don’t Follow Diets That Could Prevent Cancer

The eating habits of most American adults aren’t in line with dietary guidelines that can reduce the risk of cancer, a new study finds.

Researchers examined data from nearly 31,000 U.S. adult participants in the annual National Health and Nutrition Examination Survey.

The analysis of what the participants ate in the 24 hours before completing the survey showed that about 63% to 73% didn’t get the recommended daily amount of fruits and vegetables and whole grains, and about 90% didn’t achieve the recommended 30 grams of fiber per day.

Nearly 70% of the participants were overweight or obese. Obese participants, who made up nearly 36% of the survey volunteers, were significantly less likely than other adults to get recommended intakes of fiber, fruit, non-starchy vegetables and whole grains.

Obese adults were also more likely to exceed the recommended 18 ounces per week of red meat and to have had fast food on the day they took part in the survey.

On average, all participants consumed more added sugars than the recommended maximum of less than 10% of overall daily calories, according to the study published recently in the Journal of the Academy of Nutrition and Dietetics.

“We’re looking at individuals to move toward a primarily plant-based type of dietary pattern rich in fruits and vegetables, whole grains and beans, peas, lentils, seeds and nuts — and cutting back on saturated fats and sodium,” said senior study author Colleen Spees, an associate professor of medical dietetics in Ohio State University’s School of Health and Rehabilitation Sciences.

“Modifying our current dietary and physical activity patterns to better align with these evidence-based guidelines over time is important to reduce the risk of noncommunicable disease and promote lifelong health and wellness,” Spees said in a university news release.

“If Americans adopt these recommendations, they can reduce their risk of obesity, cancer, cardiovascular disease, stroke and high blood pressure,” she added.

The guidelines are from the American Institute for Cancer Research, the American Cancer Society, and the U.S. Department of Agriculture.

Even if you can’t meet all the guidelines, following some is better than ignoring them altogether, Spees said.

For example, eat out at fast food restaurants less often and find tasty ways to incorporate more vegetables, grains and beans into meals prepared at home, she suggested.

Source: HealthDay

Mughal-style Fried Lamb

Ingredients

1 lb lamb
1/2 cup oil
2 teaspoons garlic
2 teaspoons ginger
2 teaspoons red chili powder
1/4 teaspoon turmeric
1 teaspoon salt

Method

  1. Wash lamb and cut into bite-size pieces.
  2. Rub all the ground spices into the meat and set aside.
  3. Using saucepan, frying pan or round bottom frying pan, heat oil well. Add meat and salt and fry until brown.
  4. If after frying until well browned, meat is still not tender, add 1/2 cup water and cook over low heat until meat is dry.

Makes 4 to 6 servings.

Source: Mughal Cuisine


Today’s Comic