Chuckles of the Day




Blind Pilot?

I was flying from San Francisco to San Diego. By the time we took off, there had been a 45-minute delay and everybody on board was ticked.

Unexpectedly, we stopped in Sacramento on the way. The flight attendant explained that there would be another 45-minute delay, and if we wanted to get off the aircraft, we would re-board in 30 minutes.

Everybody got off the plane except one gentleman who was blind. I noticed him as I walked by and could tell he had flown before because his Seeing Eye dog lay quietly underneath the seats in front of him throughout the entire flight. I could also tell he had flown this very flight before because the pilot approached him and, calling him by name, said:

“Keith, we’re in Sacramento for almost an hour. Would you like to get off and stretch your legs?”

Keith replied, “No thanks, but maybe my dog Butch would like to stretch his legs.”

All the people in the gate area came to a completely quiet standstill when they looked up and saw the pilot walk off the plane with the Seeing Eye dog!

. . . . . . . The pilot was even wearing sunglasses.

. . . . . . . People scattered.

. . . . . . . They tried to change planes AND airlines!

* * * * * * *

Fun Management Aptitude Test

Management IQ Test Question 1

How do you put a giraffe into a refrigerator?

The correct answer is: Open the refrigerator, put in the giraffe and close the door.

This question tests whether you tend to do simple things in an overly complicated way.

Management IQ Test Question 2

How do you put an elephant into a refrigerator?

The wrong answer is: Open the refrigerator, put in the elephant and close the door.

The correct answer is: Open the refrigerator, take out the giraffe, put in the elephant and close the door.

This tests your ability to think through the repercussions of your actions.

Management IQ Test Question 3

The Lion King is hosting an animal conference, all the animals attend except one. Which animal does not attend?

The correct answer is: The Elephant. The Elephant is in the refrigerator.

This tests your memory.

OK, even if you did not answer the first three questions, correctly, you still have one more opportunity to show your abilities.

Management IQ Test Question 4

There is a broad, deep river you must cross. But it is inhabited by hungry crocodiles. How do you manage it?

The correct answer is: You swim across. All the Crocodiles are attending the Animal Meeting!

This tests whether you learn quickly from your mistakes.

According to a Leading Management Consulting firm, around 90% of the management professionals they tested got all 4 questions wrong.

(But many preschoolers got several correct answers.)

This conclusively disproves the theory that most management professionals have the brains of a four year old.




 

 

 

 

The Real Reason Chicagoans Don’t Put Ketchup On Their Hot Dogs

Maria Scinto wrote . . . . . . . . .

If you visit Chicago, there are several things you absolutely must do: stroll the Magnificent Mile, catch a Cubs game at Wrigley Field, and order one of the city’s signature Chicago dogs. There are also several things you should absolutely not do: make any mention of the New York City skyline being more impressive, root for the St. Louis Cardinals, or ask for ketchup with your hot dog.

Seriously, don’t even think about ruining a Chicago dog with ketchup. Former First Chicagoan Barack Obama once famously stated that ketchup does not belong on a hot dog once you’re past 8 years old. Legendary Chicago newspaper columnist Mike Royko did admit that, if anyone wanted to put ketchup on their hot dog, they would have the right to do so, but went on to clarify his opinion: “It is also their right to put mayo or chocolate syrup or toenail clippings or cat hair on a hot dog. Sure, it would be disgusting and perverted, and they would be shaming themselves and their loved ones. But under our system of government, it is their right to be barbarians” (via Chicago PBS affiliate WTTW).

So why are Chicagoans so up in arms at the thought of anyone defiling their beloved hot dog? While there is no definitive reason, Grub Street states that the Chicago-style hot dog simply does not need ketchup and that the addition of this unnecessary condiment ruins the already-perfect flavor balance.

Why ketchup ruins Chicago dogs

If you haven’t already been initiated into the Chicago dog cult, you may be in need of a little explanation regarding the components of this delicacy. According to Chicago’s NPR station WBEZ, a true Chicago dog consists of an all-beef wiener in a steamed poppy seed bun topped with seven classic condiments: yellow mustard, chopped onions, sweet pickle relish, tomato slices (exactly two of these), sport peppers (two of these, as well), a dill pickle spear, and a sprinkling of celery salt.

Bruce Kraig, author of Man Bites Dog and Hot Dog: A Global History, offers an explanation of why no ketchup is needed: “If you consider what’s on a Chicago hot dog, it is hot, sour, salty, sweet — all together, with crunchy vegetables, set in a soft bun. So, it’s a symphony of textures and flavors unmatched anywhere. If you put ketchup on, it will kill everything.” Nick Kindelsperger of Grub Street concurs, going on to say, “When perfectly portioned, the seven toppings on a traditional Chicago-style hot dog […] combine to create something like a less-sweet ketchup.”

So there you have it, ketchup on a Chicago-style hot dog is superfluous and just plain wrong. You have been warned: Do not ask for it, lest you find yourself tossed into Lake Michigan… although, should you make it to the opposite shoreline, you may be relieved to know that MLive says it’s perfectly acceptable to slather ketchup all over your Michigan meat pasty.

Source: Mashed


Read also at New York Times:

Welcome to Chicago, Hot Dog Town, U.S.A. . . . . .

 

 

 

 

Asian-style Set Meal of Otoya Japan

Fried Chicken with Sweet Chili Sauce

The price is 930 yen (tax included).

Otoya Aomori Restaurant

 

 

 

 

Vitamin K Prevents Cell Death: a New Function for a Long-known Molecule

A team of researchers located at Helmholtz Munich reports on a novel function of vitamin K, which is generally known for its importance in blood clotting. The researchers discovered that the fully reduced form of vitamin K acts as an antioxidant efficiently inhibiting ferroptotic cell death.

Ferroptosis is a natural form of cell death in which cellular iron plays an important role and which is characterized by the oxidative destruction of cellular membranes. In addition, the team identified FSP1 as the warfarin-insensitive enzyme reducing vitamin K, the identity of which had been postulated but remained unknown for more than half a century. During the last years, ferroptosis has been implicated as a driver of Alzheimer’s disease and acute organ injuries among many other diseases. Thus, the present findings put forward the concept that vitamin K treatment might be a new powerful strategy to ameliorate these ferroptosis-related diseases.

Vitamin K is a potent ferroptosis suppressor

Since ferroptosis prevention is considered a highly promising approach for the therapy of many degenerative diseases, new mechanisms and compounds regulating ferroptosis are extensively being explored. To identify these new molecules, a team of researchers led by Dr. Eikan Mishima and Dr. Marcus Conrad, both from the Institute of Metabolism and Cell Death at Helmholtz Munich, along with collaborators from Tohoku University (Japan), University of Ottawa (Canada) and Technical University of Dresden (Germany), systematically studied a number of naturally occurring vitamins, as well as their derivatives. “Surprisingly, we identified that vitamin K, including phylloquinone (vitamin K1) and menaquinone-4 (vitamin K2), is able to efficiently rescue cells and tissues from undergoing ferroptosis” Dr. Eikan Mishima, first author of the study explained.

Unraveling the long sought-after vitamin K reducing enzyme FSP1

In 2019 a team of researchers around Dr. Marcus Conrad already identified an enzyme as a novel and strong inhibitor of ferroptosis : ferroptosis suppressor protein-1, short FSP1. The research team now found that the fully reduced form of vitamin K (i.e., vitamin K hydroquinone) acts as a strong lipophilic antioxidant and prevents ferroptosis by trapping oxygen radicals in lipid bilayers. In addition, they identified that FSP1 is the enzyme that efficiently reduces vitamin K to vitamin K hydroquinone, thereby driving a novel non-canonical vitamin K cycle. Since vitamin K is critically involved in blood clotting processes, the team further showed that FSP1 is responsible for the vitamin K-reduction pathway insensitive against warfarin, one of the most commonly prescribed anticoagulants.

Breakthrough in understanding vitamin K metabolism

Unraveling the identity of this enzyme solved the last riddle of vitamin K metabolism in blood clotting and elucidated the molecular mechanism of why vitamin K constitutes the antidote for overdosing of warfarin. “Our results therefore link the two worlds of ferroptosis research and vitamin K biology. They will serve as the stepping stone for the development of novel therapeutic strategies for diseases where ferroptosis has been implicated“, Dr. Marcus Conrad highlighted. In addition, since ferroptosis most likely constitutes one of the oldest types of cell death, the researchers hypothesize that vitamin K might be one of the most ancient types of naturally occurring antioxidants. “Thus, new aspects of the role of vitamin K throughout the evolution of life are expected to be unveiled” Dr. Marcus Conrad explained.

Source: Helmholtz Zentrum München

 

 

 

 

Lemongrass Pork Chop

Ingredients

1 lb boneless pork chops
1/2 onion
4 lettuce leaves
2 stalks lemongrass
4 cloves garlic
4 cloves shallot

Marinade

1/4 tsp ground black pepper
1/4 tsp five spices powder
3 tbsp fish sauce
1/4 tsp salt
1/4 tsp granulated sugar
1 tsp sesame oil
2 tbsp oi

Method

  1. Wash pork chops. Wipe dry and tenderize with the back of a chopping knife.
  2. Shred onion. Stir-fry with oil until cooked.
  3. Wash lettuce. Drain and wipe dry. Arrange on the serving plate.
  4. Mix marinade ingredients in a small bowl.
  5. Trim hard tissue off lemongrass. Chop together with shallot and garlic into mince. Add to the marinade. Mix well and marinate pork chops for 3 hours.
  6. Wipe away marinade ingredients. Fry pork chops with oil in a pan over low heat until both sides turn light brown and fully-cooked. Place them over the lettuce leaves. Garnish with fried onion before serving.

Source: Vietnamese Cuisine


Today’s Comic